TripleTOF® 5600+ System

A mass spectrometry system that integrates the highest levels of qualitative exploration, rapid profiling & quantitation workflows on a single platform.
A mass spectrometry system that integrates the highest levels of qualitative exploration, rapid profiling & quantitation workflows on a single platform.
A mass spectrometry system that integrates the highest levels of qualitative exploration, rapid profiling & quantitation workflows on a single platform.
Mass Spectometer-AB SCIEX TripleTOF® 5600+ System
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For research use only. Not for use in diagnostic procedures.

The AB SCIEX TripleTOF® 5600+ System is an innovative breakthrough in LC/MS/MS performance that uniquely integrates comprehensive, qualitative exploration, rapid profiling, and high-resolution quantitation workflows on a single platform. It combines highest-sensitivity detection, high resolution with the fastest acquisition speeds, and stable mass accuracy over days of acquisition.

Expanding upon the capabilities of TripleTOF® Technology, the 5600+ System provides broader applicability in pharmaceutical development and a new paradigm in proteomics research.

Featuring:

  • MS/MSALL with SWATH™ Acquisition – enabling comprehensive MS/MS quantitation in proteomics
  • Tools for 21 CFR 11 Compliance – in Analyst® TF 1.6 and MultiQuant™ Software, bringing the power of accurate mass to regulated bioanalysis
  • Optional SelexION™ Technology – for an additional dimension of separation
  • High resolution at unparalleled speed with 10 msec accumulation time
  • EasyMass™ Accuracy – without constant recalibration, over 50 hours of continuous LC/MS operation provides stable mass accuracy.
  • SmartSpeed™ 100Hz Acquisition – delivering high resolution for high-speed chromatography with up to 100 spectra in a second – even in Information-Dependent Acquisition (IDA) mode
  • Most sensitive, high-resolution system – lowest limits of quantitation (LOQ) for a high-resolution system and equivalent to high-performance triple quadrupoles

 

Status: Available Item status information

 

The AB SCIEX TripleTOF® 5600+ System is the next generation in quadrupole TOF technology. Combining the best-in-class front end of the Triple Quad™ 5500 System with the Accelerator TOF™ Analyzer, this instrument adds high resolution at the speed and sensitivity needed to give %CVs and limits of quantitation (LOQ) equivalent to those of high-end triple quadrupoles.

Now for the first time, pharmaceutical, academic, and analytical testing scientists can integrate comprehensive, qualitative exploration, rapid profiling, and high-resolution quantitation of low-abundance analytes in very complex matrices – all on a single platform.

FeatureBenefit
MS/MSALL with SWATH™ AcquisitionQuantitative MS/MS data that rivals triple quadrupole sensitivity and precision for every component in complex samples.  And... a complete digital archive of all precursor and product ions in a sample, for unlimited retrospective interrogation without the need to re-acquire data.
21 CFR 11 Compliance ModuleSoftware tools that support digital record-keeping and electronic signatures, enabling the use of TripleTOF® Technology in a regulated environment.
Highest sensitivity with QJet® Ion Guide and Accelerator TOF™ AnalyzerLow-abundance analytes easily discovered, identified, and quantified
SmartSpeed™ 100Hz AcquisitionThe fastest, high-resolution system that generates more high-quality information from every sample, even when using fast chromatography
EasyMass™ AccuracyAchieves high mass-accuracy without continuous recalibration, making it the easiest-to-use system for routine accurate mass.
One-touch productivity softwareIncreases productivity by facilitating powerful workflows to create information out of data
High resolution at up to 100 spectra per secondDefinitive identification at high speed even when using fast chromatography
Magnetic levitation (MagLev) turbo pumpsNew level of reliability for reduced cost of ownership and virtually silent running for a better lab environment.
Explore Workflow 5600 Explore Workflow thumbnailExplore complex samples in greater depth: Select up to 50 precursors per second – and generate high resolution and high mass-accuracy MS/MS data using powerful IDA (Information-Dependent Acquisition) algorithms and high-resolution, accurate-mass MS and MS/MS.
Profile Workflow
AB SCIEX TripleTOF™ 5600 profile workflow thumbnail
Profile samples for quant and qual in a single run: Quantify virtually every compound in the sample with high-resolution MS quantification and fast chromatography; confirm compound identity with high-resolution, accurate-mass MS/MS; and then mine the data for the information you need.
Quantify Workflow AB SCIEX TripleTOF™ 5600 System quantify workflow thumbnailQuantify analytes with high-resolution MRM transitions for highest specificity and confidence: Obtain high resolution at high and low masses in the same spectrum for high-resolution, MRM-like quantification. The LOQ's and dynamic range are equivalent to high-performance triple quadrupoles. Cycle times are as low as 10 msec and generate superior peak definition, even with fast LC separations. Quantification requires little optimization, and you can choose multiple fragments per precursor from the acquired full-scan MS/MS data.