BioAnalyst™ Software

BioAnalyst™ Software
BioAnalyst™ Software
BioAnalyst™ Software
BioAnalyst™ Software
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BioAnalystTM Software is a comprehensive, fully integrated set of data processing tools within Analyst® Software for the identification and characterization (e.g. post-translational modifications) of peptides and proteins using mass spectrometry data. 

  • Reconstruction tools for manual and automated molecular weight determination from LC/MS, MS and MS/MS data
  • Peptide mapping tools for automated matching of LC/MS data to predicted peptides in a known protein sequence including a Protein Editor for performing virtual digestions with modifications and direct links back to raw MS data
  • Proprietary de novo sequencing algorithm for automated sequencing of peptides from unknown proteins including a Peptide Editor for computing fragment ion masses of peptides which can be directly linked to raw MS/MS data for labeling and data presentation
  • PepSeaTM Server from Protana provides single spectrum database search capabilities using peptide molecular weights, peptide fragments, sequence tags, amino acid sequence, protein name and accession number
  • Data Dictionary, the single source for all chemical information, provides a dynamically linked molecule editor to easily define modifications, custom amino acids, adducts, nucleic acids, and cleavage agents
  • Supports QTRAP® Systems, Triple Quad Systems, and the TripleTOFTM 5600 System

 

Status: Available  Item status information

 

Confidently Identify and Characterize Unknown Proteins

The suite of tools supplied in BioAnalystTM Software allows full identification and characterization of proteins and peptides.  For intact molecular weight analysis, BioAnalyst software provides several powerful tools for deconvolution and reconstruction of multiply-charged electrospray data, including Bayesian Protein Reconstruct and Bayesian Peptide Reconstruct for accurate, precise MW determination of large and small proteins and peptides, in addition to Peak Score Reconstruct for faster analysis and Manual Reconstruct for full user interaction with the data.  The proprietary de novo sequencing algorithm provides automated sequence and sequence tag generation to confidently identify and characterize unknown proteins and peptides from MS/MS fragment data.  Also included are semi-automated and manual tools for "walking down" sequences and confidently assigning residues. For mapping, the peptide mapping tools allow straightforward matching of theoretical peptides with experimental MS data.  Theoretical peptide map generation is achieved using an interactive Protein Editor Window that allows in-silico digestion using a broad selection of enzymes, in addition to considering many pre-programmed or user-added post-translational modifications from the Data Dictionary.  And with the Data Dictionary, configuring new enzymes, amino acids, or modifications is straightforward.  Whether your application is accurate protein/peptide molecular weight determination, protein identification, peptide mapping, characterization of post-translational modifications, or de novo protein sequencing, BioAnalyst software's powerful protein chemistry tools will efficiently solve complex biological problems and boost your proteomics initiative.

BioAnalystTM software is provided "as is" without warranty or condition of any kind, including but not limited to the implied warranties or conditions of merchantable quality and fitness for a particular purpose.