LightSight® Software

Mass Spectrometry Software-LightSight® Software
Mass Spectrometry Software-LightSight® Software
Mass Spectrometry Software-LightSight® Software
Mass Spectrometry Software-LightSight® Software
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LightSight® Software is the ultimate tool for finding metabolites. In a few simple steps, highly optimized acquisition methods can be created to detect metabolites with unprecedented effectiveness. This allows for open access metabolite identification experiments on a QTRAP® system with minimal operator training. The streamlined acquisition process gives ADME Scientists rapid and highly relevant results. LightSight® software makes the work of identifying metabolites more efficient than ever, with a workspace that supports quick, effective decision-making. LightSight® software's exceptionally clear data display eliminates the need for tedious visual comparison of printouts. Non-mass spectrometric analog data (e.g. UV- or radioactive-detector chromatograms) can be simultaneously analyzed in LightSight® software v2.2.1, giving one the ability to correlate MS-based structural information with quantitative analog data.

Trial Software Downloads
To download a trial version and obtain license keys, visit our LightSight® Trial Software Download Registration Site
  • Designed with a simple, intuitively appealing and easy-to-use interface, so that you can spend your time studying metabolism, and not software.
  • Makes creation of even the most complex acquisition method straightforward and intuitive.
  • Simple, clear data processing in a workspace that supports quick, effective decision-making which makes the work of identifying metabolites more efficient than ever.
  • Exhaustive sets of biotransformations are built into the software, or you can build custom biotransformation sets.
  • Predicted MRM (pMRM) methods can be created automatically using LightSight® software and imported directly to the QTRAP® instrument for rapid analysis
  • Easily create methods for the QTRAP® 5500 system with multiple survey scans in a single step. Multiple Survey Scan methods are especially useful for sensitive detection of phase II conjugated metabolites.
  • Seamlessly create data acquisition methods based on the structure of the drug, and analyze and mine the resulting data.
  • Enables the coupling of sensitive triple quadrupole mode survey scans, such as neutral loss or precursor ion, with highly sensitive full-scan MS/MS data for structural characterization.
  • Non-mass spectrometric analog data (e.g. UV- or radioactive-detector chromatograms) can be simultaneously analyzed, giving one the ability to correlate MS-based structural information with quantitative analog data.

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Increased Metabolite Detection LightSight® software creates highly optimized acquisition methods which allows for increased metabolite detection. In a few simple steps, acquisition methods can be created to detect metabolites with unprecedented effectiveness. This allows for open access metabolite identification experiments on a QTRAP® system with minimal operator training The streamlined acquisition process gives ADME Scientists rapid and highly relevant results. LightSight® software creates compound specific predicted MRM-IDA methods (pMRM-IDA) which increases metabolite detection significantly over traditional theoretical MRM-IDA methods. Detect even lower level metabolites with MRM specificity and sensitivity and simultaneously and collect high quality MS/MS data on any detected peaks with the QTRAP® 5500 System.

Multiple Survey Scan Methods LightSight® Software v2.2.1 enables you to easily create methods for the QTRAP® 5500 system with multiple survey scans in a single step, Multiple Survey Scan methods are especially useful for sensitive detection of phase II conjugated metabolites. The hardware functionalities of the QTRAP® 5500 systems are fully enabled by LightSight® Software v2.2.1, which can be used to create data acquisition methods based on the structure of the drug, and seamlessly analyze and mine the resulting data. This enables the coupling of sensitive triple quadrupole mode survey scans, such as neutral loss or precursor ion, with highly sensitive full-scan MS/MS data for structural characterization.
Non-mass spectrometric analog data (e.g. UV- or radioactive-detector chromatograms) can be simultaneously analyzed in LightSight® software v2.2.1, giving one the ability to correlate MS-based structural information with quantitative analog data. This unique combination of features makes high productivity metabolite identification possible using the QTRAP® 5500 System with LightSight® software.

Intuitive Method Building LightSight® software is the right tool regardless of how you perform MS/MS acquisition. MS/MS data is easily acquired, either simultaneously with survey data, using information dependant acquisition (IDA), or in a separate run, after analyzing the survey data. The Acquire MS/MS Data wizard creates sophisticated multi-period, multi-experiment methods that often collect MS/MS data for all of a compound's metabolites in a single injection.

Simple, Clear Data Processing LightSight® software makes the work of identifying metabolites more efficient than ever, with a workspace that supports quick, effective decision-making. Overlaid extracted ion chromatograms (XICs) of the sample and control make chromatographic peaks instantly distinguishable from noise. Adjacent and aligned display of the parent and metabolite MS/MS spectra makes spectral similarities and differences immediately obvious. LightSight® software's exceptionally clear data display eliminates the need for tedious visual comparison of printouts. And now, in version 2.2.1 you can save your own processing parameters, which makes analysis of large sets of data easier and faster than ever.

Intuitive design, Powerful help LightSight® software is designed with a simple, intuitively appealing and easy-to-use interface, so that you can spend your time studying metabolism, and not software. Exhaustive sets of biotransformations are built into the software, or you can build custom biotransformation sets of your own based on what you already know about your candidate compound. Predicted MRM (pMRM) methods can be created automatically using LightSight® software and loaded directly to the QTRAP® instrument for rapid analysis. The ability of pMRM to predict a comprehensive list of transitions allows for the detection of a number of interesting metabolites. Next generation metabolite in silico prediction via LightSight® software is a perfect complement to the capabilities of the AB SCIEX QTRAP® 5500 and allows even novice metabolite investigators to achieve complete results easily.

Powered by ClearcoreTM Application Foundation LightSight® Software is the first application to be powered by the ClearcoreTM Application Foundation. The ClearcoreTM foundation provides the power for solid, easy-to-use software applications from AB SCIEX.

For Research Use Only. Not for use in diagnostic procedures.